AFFINITY PURIFICATION OF HUMAN FACTOR H ON POLYPEPTIDES DERIVED FROM STREPTOCOCCAL M PROTEIN: ENRICHMENT OF THE Y402 VARIANT.

Affinity purification of human factor H on polypeptides derived from streptococcal m protein: enrichment of the Y402 variant.

Recent studies indicate that defective activity of complement factor H (FH) is associated with several human diseases, suggesting that pure FH may be used for therapy.Here, we describe a simple method to isolate human FH, based on the specific interaction between FH and the hypervariable region (HVR) of certain Streptococcus pyogenes M proteins.Spe

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Hmgcr in the corpus allatum controls sexual dimorphism of locomotor activity and body size via the insulin pathway in Drosophila.

The insulin signaling pathway has been implicated in several physiological and developmental processes.In mammals, it controls expression of 3-Hydroxy-3-Methylglutaryl CoA Reductase (HMGCR), a key enzyme in cholesterol biosynthesis.In insects, which can not synthesize cholesterol de novo, the HMGCR is implicated in the biosynthesis of juvenile horm

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Beach erosion and nest site selection by the leatherback sea turtle Dermochelys coriacea (Testudines: Dermochelyidae) and implications for management practices at Playa Gandoca, Costa Rica

Leatherback sea turtles (Dermochelys coriacea) nest on dynamic, erosion-prone beaches.Erosive processes and resulting nest loss have long After Shaves been presumed to be a hindrance to clutch survival.In order to better understand how leatherbacks cope with unstable nesting beaches, I investigated the role of beach erosion in leatherback nest site

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